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Computational Scientist, Origin & Evolution of Life

Dayhoff Labs

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Salary
Salary not listed
Location
Cambridge, MA
Employment type
Full Time
Posted
Today

Skills & Requirements

In Silico

Description

About usWe're reverse-engineering the origin of life — one of the great unsolved problems in science, and one we think AI finally makes tractable. We believe that understanding this transition, from geochemistry to biochemistry, will let us orchestrate molecular networks and build systems that are more capable, adaptive, efficient, and intelligent.If we succeed, the applications are vast: from catalysis and green synthesis to ab initio synthetic biology and programmable matter. Understanding and harnessing these processes could let ten billion of us thrive on this planet — and let us dream that diverse life keeps evolving and thriving beyond it.We're a small, diverse team of AI engineers, computational scientists, and bench scientists. We hold ourselves to the rigor of a research institute, but we ship like an engineering firm. Global team, HQs in Cambridge, MA and London, UK.The roleYou'll run your own research line inside our central bet: that the origin of life is the missing chapter of biochemistry — the unfilled gap between geochemistry and modern enzymology. Questions we're interested in include:How did catalysts emerge from prebiotic chemistry, and what does that say about the enzyme fitness landscape now? What did the reaction networks before biochemistry look like? How do thermodynamic constraints shape complex chemical systems, and what drove enzymes toward specificity? What you'll doDrive an independent research programme to insight and publication-quality results within our origins-of-life missionPursue questions spanning prebiotic catalysis, chemical reaction networks, thermodynamic constraints, and the evolution of enzymatic specificityCollaborate closely with AI researchers, computational chemists, and wet-lab scientistsEssential experiencePhD and publication record in computational biology, computational chemistry, systems biology, chemical engineering, or an adjacent fieldReal depth in at least one of: chemical reaction network modelling; ML for molecular systems; computational biochemistry (QM/MD, reaction or catalysis modelling); evolutionary modelling (phylogenetics, ancestral reconstruction, population genetics); non-equilibrium thermodynamics or statistical physicsAbility to drive a research programme to insight and publication-quality research (this matters more than specific research experience)Highly preferredCross-disciplinary fluency across more than one of the depth areas aboveA track record of independent, self-directed researchLogisticsCompensation is highly competitive. We're also able to sponsor visas for the right candidate.Find more English Speaking Jobs in United Kingdom on Arbeitnow

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Source: arbeitnow (computational-scientist-origin-evolution-of-life-cambridge-ma-351734)View original listing ↗